AKT Kinase Inhibitor - Search Results

About 4 results found for searched term "AKT Kinase Inhibitor" (0.132 seconds)

Cat.No.	Name	Target
M14833	AKT Kinase Inhibitor	Akt
	AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity.
M27611	PF-AKT400	Akt
	AKT protein kinase inhibitor
	PF-AKT400 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM).
M7690	ML-9	Autophagy
	ML-9 is a potent, selective Akt kinase inhibitor that inhibits myosin light chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity. It acts on MLCK, PKA and PKC with Ki values of 4, 32 and 54 μM, respectively. In addition, ML-9 induces autophagy by stimulating the formation of autophagosomes and inhibiting their degradation.
M28378	Vevorisertib	Akt
	ARQ 751
	Vevorisertib (ARQ 751) is an orally active, potent and selective pan-AKT serine/threonine kinase inhibitor against AKT1 (IC50=0.55 nM), AKT2 (IC50=0.81 nM), and AKT3 (IC50=1.31 nM). Vevorisertib, as a single agent or in combination with other anti-cancer agents, can be used for the research of solid tumors with PIK3CA / AKT / PTEN mutations.